• Precision medicine is a valuable new tool to aid diagnosis and prescription
• A new generation of DNA sequencing technology makes it possible to obtain complete genomes for individual patients.
• Large-scale genome-wide surveys of associations between DNA markers and disease conditions are a key resource in this process.
• Individual patients will be able to get health advice based on their personal Polygenic Risk Score (PRS).
• All PRS statistics depend on knowledge about ancestry.
• In Aotearoa/New Zealand engagement with, or work led by, Māori and Pasifika voices is required.
• There are already existing examples to show how widely and successfully this programme has been adopted overseas.